combinatorial libraries造句
例句与造句
- Early work by Sanders et al . employed transesterification to generate dynamic combinatorial libraries.
- Combinatorial libraries were designed and used to select and evolve new proteins that would have higher affinity for their targets, improved stability and ease of production.
- She has also significantly contributed to the development of compound collections and combinatorial libraries which investigators can use to develop and compare measures of molecular similarity and diversity.
- The lead compound was developed from a " hit " compound discovered through a resin-bound dynamic combinatorial library screen, and the structure is shown at right.
- For example, Lehn et al . used this method to create a dynamic combinatorial library of imine inhibitor from a set of amines and a set of aldehydes.
- It's difficult to find combinatorial libraries in a sentence. 用combinatorial libraries造句挺难的
- His recent academic research centred on engineering of antibodies for application in health care, management of environmental pollution, and the derivation and use of novel combinatorial libraries.
- Xu " et al " have generated combinatorial libraries based on these pre-BCR proteins in which diverse heavy chains are paired with a fixed surrogate light chain components.
- Monobodies are generated from combinatorial libraries in which portions of the FN3 scaffold are diversified using molecular display and directed evolution technologies such as phage display, mRNA display and yeast surface display.
- However, their subsequent investigations identified that both the disulfide and hydrazone covalent bonds exhibit effective component exchange processes and so present a reliable means of generating dynamic combinatorial libraries capable of thermodynamic templation.
- In 2002, Sanders and coworkers published the use of dynamic combinatorial library technique to construct a receptor and in 2003 they employed the technique to develop a catalyst for Diels-Alder reaction.
- Unlike comparable methods for pyridine synthesis, the Kr鰄kne synthesis benefits from being a high-yielding one pot synthesis, which ultimately allows for abbreviation of synthetic pathways and further simplifies combinatorial library cataloging.
- "to provide novel binding proteins with affinities for their targets which are much higher than those provided by traditional monoclonals through the use of antibody phage display libraries and combinatorial libraries based upon novel scaffolds.
- He has devised a range of novel methods on the generation of N-acyl iminium ions which combinatorial libraries of these compounds have generated and screened for active GPCR substances in cell-based on-bead screening.
- Although searching the entire chemical universe may be a theoretically interesting problem, more practical VS scenarios focus on designing and optimizing targeted combinatorial libraries and enriching libraries of available compounds from in-house compound repositories or vendor offerings.
- Peptide combinatorial libraries of tri-, tetra-, and pentapeptides with various amino acid compositions were screened as potential sources of inhibitors, to see if it serves as either pure or mixed competitive inhibitor for the hAANAT enzyme.
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